Allergic Asthma – Parents Of Allergic Children http://parentsofallergicchildren.org/ Fri, 17 Sep 2021 19:13:01 +0000 en-US hourly 1 https://wordpress.org/?v=5.8 https://parentsofallergicchildren.org/wp-content/uploads/2021/06/icon-5.png Allergic Asthma – Parents Of Allergic Children http://parentsofallergicchildren.org/ 32 32 Improve the air quality inside your home https://parentsofallergicchildren.org/improve-the-air-quality-inside-your-home/ https://parentsofallergicchildren.org/improve-the-air-quality-inside-your-home/#respond Fri, 17 Sep 2021 15:54:00 +0000 https://parentsofallergicchildren.org/improve-the-air-quality-inside-your-home/ CHARLOTTE, North Carolina – Sponsored by: Charlotte, NC – This article involves commercial content. The products and services presented appear as paid advertising. With Covid-19, breathing clean air has become more important than ever. It is really important for allergies, asthma and respiratory problems. And if there are seniors at home, you want to make […]]]>

CHARLOTTE, North Carolina – Sponsored by:

Charlotte, NC – This article involves commercial content.

The products and services presented appear as paid advertising.

With Covid-19, breathing clean air has become more important than ever. It is really important for allergies, asthma and respiratory problems. And if there are seniors at home, you want to make sure the air they breathe is clean. Lauren Acosta Huckleberry with Acosta Heating Cooling and Electrical has information on two products that will improve your air quality.

First of all, Phenomenal Aire is a great product. It works in conjunction with your existing air filters and it is a local product made here in Indian land. It works by creating billions of negative and positive ions. Your HVAC system then distributes them throughout your living spaces. These ions are attracted to the protein membrane of the virus and work to disrupt these proteins and envelop the virus, thus neutralizing the virus. In addition to reducing the risk of COVID-19 viruses in the air, Phenomenal Aire offers these advantages: Reduces unpleasant odors, No maintenance or spare parts No harmful by-products Reduces allergens.

The next Lennox PUREAIR product is more advanced. Lennox PUREAIR features the Lennox Healthy ClimateTM Carbon Clean 16 R air filter which provides hospital grade filtration. The PUREAIR system will replace the air filters in your home – no need to change your air filters! All air filtration occurs in the PUREAIR system and only requires maintenance once a year. This removes over 99% of the COVID-19 virus from the air, in addition to smaller viruses, bacteria and fungal spores. With zero ozone production and maximum air flow, Lennox PUREAIR provides constant, clean and perfect air for your home.

Remember, this is also the time of year when you have the batteries in your smoke detectors and carbon monoxide detectors replaced. Remember, September is a great time to have your furnace checked. Acosta wants to make sure there are no leaks in your oven or silent killer carbon monoxide emissions. Acosta is hosting a $ 59 heater and security check and tune up through September. That’s a 40% savings on your Heating Security Check and you’ll start the fall and winter months on the right foot. For more information, visit AcostaInc.com


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Back on September 17 https://parentsofallergicchildren.org/back-on-september-17/ https://parentsofallergicchildren.org/back-on-september-17/#respond Fri, 17 Sep 2021 04:01:00 +0000 https://parentsofallergicchildren.org/back-on-september-17/ 100 years ago: 1921 The 79th Oxford County Agricultural Society Exhibition will be held on their grounds between Norway and southern Paris on September 20, 21 and 22. If the weather is unfavorable, the fair will be postponed throughout the week. On the program, a baby show, several good trots and gaits, drawing horses, baseball […]]]>

100 years ago: 1921

The 79th Oxford County Agricultural Society Exhibition will be held on their grounds between Norway and southern Paris on September 20, 21 and 22. If the weather is unfavorable, the fair will be postponed throughout the week. On the program, a baby show, several good trots and gaits, drawing horses, baseball games and an orchestral concert.

50 years ago: 1971

The Auburn-Lewiston Maine Marine Explorers Dive Club will hold its first fall meeting tonight at the Auburn Lewiston YMCA, with the meeting starting at 6:45 p.m. is open to anyone interested in taking scuba diving courses or joining the Explorers Club. Registration for the ten-week, 82-hour course, starting September 23, is now open. The diving class which is led by; Marcel Corriveau and Donald J. Bernard, both certified instructors. has a limited enrollment of 12 students. A field visit to Casco Bay on September 26 will be discussed at the meeting.

25 years ago: 1996

The first-ever Asthma Health Show will be held Saturday from 9:30 am to 3:30 pm in Lepage Conference Center, 99 Campus Ave., St. Mary’s Regional Medical Center. “We’re planning a fun day for adults and kids,” said Maryann Cormier, asthma instructor and one of the Asthma Fair coordinators, “but we’ll also be presenting some important information about asthma and how to manage the condition. ”The Asthma Fair is designed for people with asthma and their families, teachers, coaches, school nurses or anyone working with people with asthma. games and face painting for children, prize drawings and exhibits with information and materials that can help asthmatics. Guest speakers include George Vraney. Physician, pulmonologist and allergist, who will speak on “Asthma and Allergies.” at 10 hours; Richard Kahn, MARYLAND, pulmonologist, “exercise-induced asthma” at 11:15 am; Andrew Carey, MD. allergist, “Managing Your Asthma” at 1:00 pm; and Linda Glass, MD, pediatrician, “L asthma in Children ”at 2:15 pm The Asthma Fair is open to the public and is sponsored by various pharmaceutical companies and the Open Airways Asthma program at St. Mary’s Regional Medical Center.

The material used in Looking Back is produced exactly as it originally appeared, although spelling mistakes and errors can be corrected.


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Morning allergies: symptoms, prevention and treatment https://parentsofallergicchildren.org/morning-allergies-symptoms-prevention-and-treatment/ https://parentsofallergicchildren.org/morning-allergies-symptoms-prevention-and-treatment/#respond Thu, 16 Sep 2021 18:59:55 +0000 https://parentsofallergicchildren.org/morning-allergies-symptoms-prevention-and-treatment/ Have you ever woken up in the morning with congestion, irritation, and red, watery eyes? If so, you could have morning allergy symptoms. There are many factors that can cause morning allergies. Usually, if your symptoms get worse in the morning, it can be caused by dust mites, which tend to settle in people’s bedding. […]]]>

Have you ever woken up in the morning with congestion, irritation, and red, watery eyes? If so, you could have morning allergy symptoms.

There are many factors that can cause morning allergies. Usually, if your symptoms get worse in the morning, it can be caused by dust mites, which tend to settle in people’s bedding. But these allergies can also be caused by pollen and animal dander.

Learn more about morning allergies, their causes, symptoms, prevention, and treatment methods.

PeopleImages / Getty Images


Common causes of morning allergies

Whether you have hay fever or a dust mite allergy, it’s common to wake up with a sneeze when you have allergies. There are several reasons that can happen, including:

  • Higher pollen counts in the morning
  • Dust mites that live in and around your bed
  • Pet dander that accumulates in your bedroom

Allergy statistics

Allergies are common and affect more than 50 million Americans each year.

Mites

As unpleasant as it may sound, dust mite allergies are not actually an allergy to dust or mites. Rather, it is the mite’s droppings that actually contain the allergen (the substance that triggers an allergic reaction). Unlike pollen allergies, dust mite allergies occur year round because they live inside your home.

Dust mites can live anywhere, but they especially like rugs, bedding, curtains, and upholstered furniture. It is not possible to eliminate the mites.

Symptoms of dust mite allergies are usually worse in the morning because you are exposed to the allergen while you sleep.

Pollen

Pollen allergy, also known as hay fever or seasonal allergic rhinitis, is one of the most common allergies. In the United States, it affects 7.7% of adults and 7.2% of children.

Plants release pollen to fertilize other plants of the same species. Pollen allergies are caused by a reaction to the pollen that plants and trees release in spring, summer, and fall.

Common pollen allergies include:

Symptoms of pollen allergies are often worse in the morning. Plus, pollen can stick to your clothes, which means you carry the allergen with you throughout the day. Plus, if you sleep with the windows open, you can be exposed to pollen overnight.

Pets

Pet allergies often occur in people who have other allergies or asthma. In fact, up to 30% of allergy sufferers are also allergic to cat and dog dander.

Cats vs. Dogs

Allergies to cats are twice as common as allergies to dogs.

People with allergies to pets react to proteins in an animal’s urine, saliva, or dander (dead skin cells). People often mistake animal hair or fur for an allergen, but this is not the case. However, animal hair or fur can carry allergens.

Symptoms of pet allergies can occur in the morning, especially if your pet is sleeping in your room with you. You can find morning allergy relief if you keep your pet out of your bedroom and change clothes before going to bed.

Mold

Mold can be found indoors and outdoors, which means you can have mold allergies year round. When a mold source is disturbed, spores are released into the air. For the allergic person, inhaling them may trigger a reaction.

Indoors, mold can be found in damp areas, such as bathrooms, kitchens and basements. Common places to find mold outdoors include:

  • Newspapers
  • Dead leaves
  • Compost
  • Grasses
  • Cereals

Symptoms of allergies in the morning

Allergy symptoms in the morning are the same as allergy symptoms at any other time of the day. However, morning allergic symptoms are sometimes more severe. They may include:

  • sneezing
  • Runny or stuffy nose
  • Tired
  • Itchy, watery eyes
  • Swollen eyes
  • Itchy ears
  • Cough

In severe cases, you may experience asthma-like symptoms. These can include difficulty breathing, wheezing, and coughing.

Cats and asthma attacks

Cats can trigger a severe asthma episode in up to 30% of people with asthma.

Diagnosis of morning allergies

Doctors diagnose allergies based on your symptoms and tests that confirm an allergic reaction. Morning allergies are diagnosed when your symptoms first appear in the morning. Diagnosis may include:

  • Medical background: Your doctor or an allergist (doctor specializing in allergies and allergic asthma) will take your medical history, including if you have a family history of allergies or asthma. The doctor will also do a physical exam.
  • Symptom assessment: Your doctor will assess your symptoms, including what triggers them and when they happen most often.
  • Allergy tests: This may include skin tests, blood tests, or both.

Skin tests

Skin tests are considered the gold standard for determining what a person is allergic to. These tests are performed in the office of an allergist. The two types of skin tests are:

  • Scratch test: Drops of an allergen are scratched on the skin, then the location is observed for a reaction.
  • Intradermal test: A small amount of the allergen is injected under the skin, then the location is observed for a reaction.

Blood tests

With a blood test, a phlebotomist takes your blood and a lab professional assesses it. They specifically look for immunoglobulin E (IgE) antibodies in response to allergens.

IgE is a type of antibody that is produced when a person is sensitized to an allergen. A specific IgE test can identify what you are allergic to.

Ways to prevent morning allergy triggers

The good news is that there are steps you can take to limit your morning allergy symptoms. Some things to try include:

  • Keep windows closed: When the pollen count is high, close the windows and use the air conditioning instead.
  • Take allergy medication: When taken before exposure to pollen, antihistamines can keep your allergy symptoms at bay.
  • Shower before bed: Showering will remove pollen from your skin and hair. Also, be sure to put on clothes that haven’t been exposed to allergens before bed.
  • Lower humidity: It can help reduce allergies to dust mites and indoor molds.
  • Clean regularly: Cover your mattress and pillows with special dust mite covers and wash your bedding in hot water every week. Also, dust hard surfaces and vacuum carpets, especially those in the bedroom.
  • Replace carpet with hard floor: Pet dander and mites love to hide in carpets. If you can’t replace all the rugs in the house, start with the one in your bedroom.

When to seek professional treatment

Often, morning allergies are a mild, sometimes seasonal, nuisance. Other times they are more severe. In this case, it is important to make an appointment with your doctor.

If lifestyle adjustments and over-the-counter antihistamines (OTC) aren’t helping, you may want to see your doctor for a formal diagnosis and treatment plan. Your doctor may recommend intranasal corticosteroids, some of which are available over the counter.

Immunotherapy (called allergy shots) can also help control allergies when it is difficult to avoid triggers. Your allergist will formulate them to help you desensitize yourself to allergens. They are particularly useful against common triggers of morning allergies.

Immediate medical attention

If you have asthma-like symptoms, such as wheezing, coughing, or difficulty breathing, see a doctor immediately.

Summary

Allergy symptoms experienced in the morning may be due to pollen, dust mites, pets, or mold. An allergist can help you identify the source of your allergy and recommend lifestyle adjustments and medications that can help manage it.

A word from Verywell

If you are looking to relieve your morning allergies, there are some things you can do. Identifying the source of your allergy is an important starting point.

Often times, people can guess what they are allergic to based on when their symptoms appear and what triggers them. However, the only definitive way to identify your allergy is with the allergy test.

You may be able to reduce your morning allergy symptoms by cleaning your bedroom and bedding often, using dust mite covers for pillows and bedding, showering before bed, removing carpet from your bedroom and keeping your windows closed at night.

Frequently Asked Questions

Can my morning allergies be cured?

Allergies, including those that show symptoms in the morning, can sometimes be cured by using allergy shots. Morning allergies can be managed with lifestyle changes, avoiding allergens, and with medication.

Do morning allergies cause headaches and other symptoms?

Yes, sinus headaches and migraines have been linked to allergies. This is because allergies can cause the sinus cavities to swell, causing pain and pressure.

How long will my morning allergies last?

The duration of morning allergies depends on their cause. If, for example, your morning allergies are caused by a seasonal pollen allergy, then your morning allergies should subside as the pollen count goes down. Plus, you can manage your symptoms by avoiding triggers or taking over-the-counter or prescription medications.


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Top 10 Best Cities In The UK To Go To If You Suffer From Allergies United Kingdom | New https://parentsofallergicchildren.org/top-10-best-cities-in-the-uk-to-go-to-if-you-suffer-from-allergies-united-kingdom-new/ https://parentsofallergicchildren.org/top-10-best-cities-in-the-uk-to-go-to-if-you-suffer-from-allergies-united-kingdom-new/#respond Tue, 14 Sep 2021 17:27:00 +0000 https://parentsofallergicchildren.org/top-10-best-cities-in-the-uk-to-go-to-if-you-suffer-from-allergies-united-kingdom-new/ Supplement Place’s EU Allergy Index revealed the list after analyzing allergy-related hospitalizations, local asthma rates and air quality. The statistics have all been counted and ranked to give each UK site an overall allergy score. Over eight million people in the UK have been diagnosed with asthma. Here are the top three places that are […]]]>

Supplement Place’s EU Allergy Index revealed the list after analyzing allergy-related hospitalizations, local asthma rates and air quality. The statistics have all been counted and ranked to give each UK site an overall allergy score. Over eight million people in the UK have been diagnosed with asthma. Here are the top three places that are considered the best places to visit that are least likely to trigger allergy symptoms.

1. Liverpool Allergy Score: 8.72

The most suitable English city for allergy-seekers looking for a vacation is Liverpool, which came out on top with an allergy score of 8.72. This coastal city has excellent air quality, scoring as low as three on the Air Quality Index, and a low local asthma rate of 6.40%.

2. Ipswich Allergy Score: 8.63

Ipswich has the second best allergy score of 8.63. This is due to a very low rate of allergy-related hospital admissions, at just 46.5 per 100,000, combined with a near-perfect Air Quality Index score of one.

3. Derby allergy score: 8.62

Derby takes third place for being good for allergy sufferers, with an allergy score of 8.62. This East Midland town has excellent air quality, having also received an almost perfect AQI score of one.

The Supplement Place team commented on how you can fight your summer allergies:

“While there are many ways to improve your health that will make the summer more enjoyable, such as exercise, eating a balanced diet, and taking the right vitamin supplements, none of them will stop you from falling victim to it. summer allergies.

You can boost your immune system to fight summer allergies by adding anti-inflammatory drugs such as fresh ginger to your daily diet and consuming local honey regularly. “

They added, “Local honey is a great option for combating hay fever because it familiarizes your body with local pollens, allowing your immune system to produce antibodies to specifically counter plants that are local to you.

“Unfortunately, the benefits of eating local honey take time to develop, so it won’t be an effective way to prevent hay fever while traveling. So, why not plan a summer trip that takes you away from it all. pollen and pollution in a place where you can breathe at ease and enjoy the warmer months in peace? “


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Eczema and the intestine-skin axis: what is the link? https://parentsofallergicchildren.org/eczema-and-the-intestine-skin-axis-what-is-the-link/ https://parentsofallergicchildren.org/eczema-and-the-intestine-skin-axis-what-is-the-link/#respond Fri, 10 Sep 2021 20:10:51 +0000 https://parentsofallergicchildren.org/eczema-and-the-intestine-skin-axis-what-is-the-link/ The human body is quite amazing. As we learn more about how the different parts interact, it becomes even more amazing. There is growing interest in how our gut and skin communicate with each other. The “intestine-skin axis” refers to all of the connections between our skin and our digestive system. Both the skin and […]]]>

The human body is quite amazing. As we learn more about how the different parts interact, it becomes even more amazing. There is growing interest in how our gut and skin communicate with each other.

The “intestine-skin axis” refers to all of the connections between our skin and our digestive system. Both the skin and the digestive tract interact with our internal and external environment. This means that they are in constant communication with the world around us and the world inside us.

Much of this communication takes place through our body’s microbiome. Our microbiome is made up of billions of bacteria, fungi, and other living things. They live in and on our bodies, mainly in our intestines and on our skin.

These microbes play an important role in our health. An imbalance in microbes in the skin or gut often affects the other. Alterations in the microbiome are observed under various health conditions. These include mental health issues, irritable bowel syndrome (IBS), diabetes, and skin issues.

Eczema is an inflammatory skin condition. People with eczema have distinct differences in their microbiomes. We are yet to discover how our microbes can be altered to promote better health. The hope is that this information can help find better treatments for eczema.

Treatment for eczema is no longer just about targeting your skin. It’s possible that changing your gut microbiome will improve your skin as well.

The constitution of the microbiome begins at birth. There is a number of factors that influence the colonies that settle in your gut and on your skin.

These include:

  • delivery method (vaginal or cesarean delivery)
  • how you were fed as an infant (breast milk or infant formula)
  • your age
  • stress
  • your genetic makeup
  • where in the world you live
  • the use of certain medications, including antibiotics

There isn’t a single healthy microbiome. A healthy person will not have the same microbiome as another healthy person.

Research noted distinct differences in the microbiome of people with certain diseases. We don’t know what happens first.

In babies and children, eczema can be an early sign of allergy risk. Eczema and allergies are both triggered by an abnormal immune response.

The immune system usually only responds to a real threat such as a virus or harmful bacteria. It will send an army of inflammatory proteins to fight an invader. With allergies or eczema, the immune system is triggered by something that shouldn’t trigger it.

Babies with eczema are more likely to develop food allergies or asthma. Allergy testing is often recommended for babies and children with eczema. Removing all allergens from the diet will often improve the skin.

Children with eczema have different skin bacteria compared to children without eczema.

Studies gut microbiome support the idea that skin and gut health are linked. Children without eczema have more gut microbiome the diversity compared to those who suffer from eczema. Greater diversity in the gut microbiome is often a sign of better health.

Sometimes children come out of eczema. In adults, especially the elderly, several changes occur naturally in the skin. This changes the skin’s microbiome to promote more beneficial bacteria. This crowds out many inflammatory bacteria associated with eczema. This may explain why some cases of eczema improve with age.

There are theories that changing the gut microbiome could improve eczema. Everyone’s microbiome is slightly different. It’s impossible to know what the “perfect” microbiome would look like to prevent or manage eczema.

There is also the continuing question of which comes first. Is something causing a change in the microbiome, leading to disease? Or is the disease causing a change in the microbiome?

Common treatments for eczema include topical creams or narrowband ultraviolet treatment. These can be found at change the skin microbiome. They promote healthy bacteria and reduce inflammatory bacteria on the skin. This relieves the symptoms of eczema.

You may have heard of fecal transplants. This is when gut bacteria from a healthy donor are introduced into someone else’s gut. This was done to restore healthy gut bacteria in people with inflammatory bowel disease (IBD) or Clostridium difficile (C. diff) infection.

Skin microbiome transplants could be the next step. Research is looking to see if it can help treat eczema. In theory, healthy skin bacteria from donors could restore balance to the skin microbiome. There is still work to be done before this becomes standard practice.

Probiotic supplements can be helpful for people with digestive symptoms. With skin and gut microbes so connected, could oral probiotics also support skin health? There are theories that changing gut bacteria with probiotics can improve skin as well. So far, there are no results to support this idea.

A 2018 Cochrane The review explored 39 randomized controlled trials on this topic. The review looked at whether oral probiotics would improve eczema. No trials have shown significant improvement in eczema with probiotic supplements.

At this point, there is no specific probiotic supplement to improve eczema. With further research, this may change.

There may be a promise with symbiotic. Symbiotic supplements include both probiotics and prebiotics. Probiotics are healthy bacteria, and prebiotics are food for probiotics. This combination can increase the chances that certain bacteria will thrive in the gut.

A Meta-analysis 2016 examined whether symbiotics could be useful for people with eczema. He has shown that specific symbiotics can help treat dermatitis in children aged 1 year and older. More research is needed to find out if symbiotics may play a role in preventing eczema.

People with eczema have more Staphylococcus aureus (S. aureus) bacteria on their skin. This bacteria is associated with greater inflammation. The more severe the eczema, the more S. aureus bacteria are present.

There are several species of beneficial bacteria that live on the skin. Many act as barriers to prevent harmful invaders from entering the body. Some bacteria actually have antimicrobial properties to block pathogens. The population of S. aureus makes it harder for beneficial bacteria to live on the affected areas of the skin.

There are things you can do to support gut health. At this point, it’s unclear exactly what the “best” gut microbiome is for eczema. People with eczema and other inflammatory conditions tend to have less diverse microbiomes.

Certain lifestyle choices can promote greater diversity in your microbiome:

  • Eat a diet high in fiber. A diet high in fiber is associated with greater diversity in your gut microbiome. Sources of fiber feed healthy bacteria in your gut. You can get fiber in your diet from whole grains, nuts, seeds, beans, vegetables, and fruits.
  • Incorporate fermented foods. Fermented foods are created using microbes. They are great sources of probiotics and can improve your gut health. Fermented foods include yogurt, kefir, tempeh, kimchi, and sauerkraut.
  • Limit alcohol consumption. Alcohol consumption has been shown to alter the gut microbiome. It can lead to the intestine dysbiosis. It’s best to cut down on alcohol if you can.
  • To manage stress. If you often feel stressed out, you know that stress can really affect how you feel. Research suggests that it may also change our microbiome. It’s unrealistic to let go of your stress completely, but finding ways to deal with it better can help.

We have billions of bacteria, fungi and other living things that live in and on our bodies. It makes up our microbiome. Most of these microorganisms live on our skin and in our intestines. These microorganisms are in constant communication. This is called the gut-skin axis.

Everyone’s microbiome is a little different, and there isn’t a perfect microbiome. There are distinct changes seen with certain conditions. People with eczema have different colonies of bacteria compared to people without eczema.

There is hope that modifying these colonies may play a role in the treatment of eczema. Many current treatments reduce inflammatory bacteria and promote the growth of beneficial bacteria. There are things you can do to support a healthy and diverse gut microbiome. It can also improve the health of the skin.


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Dupilumab reduces severe exacerbations in patients with type 2 asthma https://parentsofallergicchildren.org/dupilumab-reduces-severe-exacerbations-in-patients-with-type-2-asthma/ https://parentsofallergicchildren.org/dupilumab-reduces-severe-exacerbations-in-patients-with-type-2-asthma/#respond Tue, 07 Sep 2021 21:00:49 +0000 https://parentsofallergicchildren.org/dupilumab-reduces-severe-exacerbations-in-patients-with-type-2-asthma/ Recent data showed that oral biologic dupilumab (Dupixent) reduced severe exacerbations such as asthma attacks and improved long-term lung function for up to 96 weeks in adults and adolescents with signs of inflammation of the lungs. type 2, regardless of the allergic phenotype. The results were presented at the 2021 International Congress of the European […]]]>

Recent data showed that oral biologic dupilumab (Dupixent) reduced severe exacerbations such as asthma attacks and improved long-term lung function for up to 96 weeks in adults and adolescents with signs of inflammation of the lungs. type 2, regardless of the allergic phenotype.

The results were presented at the 2021 International Congress of the European Respiratory Society (ERS).

Dupilumab is a fully human monoclonal antibody capable of blocking the shared receptor component of interleukin-4 and IL-13, the main drivers of type 2 inflammation in various diseases.

Researchers led by Eric D. Batemen, MD, University of Cape Town Lung Institute, South Africa, noted that dupilumab significantly reduced severe asthma exacerbations and improved pre-bronchodilator FEV1 compared to placebo, which was recorded in the LIBERTY ASTHMA QUEST data.

In this study, the researchers also found that 29.6% (n = 103) of patients treated with dupilumab had no exacerbation at week 24, compared to 7.7% (n = 15) of the placebo group, with an ACQ-5 score of less than 1.5. and a post-bronchodilator FEV1 of at least 80%, which was classified as clinical remission.

In the recent study, Batemen and colleagues analyzed the QUEST / TRAVERSE study population with and without evidence of an allergic asthma phenotype at baseline and with characteristics of a type 2 inflammatory phenotype according to the criteria. GINA.

The study

Batemen and investigators recruited LIBERTY ASTHMA QUEST trial participants, all ages 12 and older.

Patients in the LIBERTY ASTHMA QUEST trial who participated in the OLE LIBERTY TRAVERSE study included patients with or without evidence of an allergic asthma phenotype, as well as blood eosinophils ≥ 150 cells / µL at baseline and FeNO ≥ 20 ppb at the beginning.

The investigators established a dupilumab group and a placebo group. Participants in dupilumab received 200 to 300 mg of the biologic every 2 weeks.

Annualized exacerbation rates in patients with type 2 asthma with and without evidence of allergic phenotypes were recorded, as well as changes in pre-bronchodilator FEV1 in these same groups.

Overall results were recorded at 96 weeks.

The results

The results of the TRAVERSE study mirrored those recorded in the QUEST study.

The annualized rates of asthma attacks in people with ≥ 150 blood eosinophils / µL were 0.32 versus 0.37 in allergy sufferers and 0.27 versus 0.30 in non-allergic people.

In addition, the mean improvement in FEV1 LS from baseline of QUEST in people with ≥ 150 blood eosinophils / µL was 0.35 L versus 0.39 L in allergy sufferers and 0.36 L versus 0.37 L in people without allergies.

Batemen and colleagues noted that dupilumab reduced the rate of exacerbation in patients with type 2 inflammatory asthma. An improvement in pre-bronchodilator FEV1 was also recorded, which was maintained through the 96 weeks of l ‘study.

As mentioned earlier, allergic phenotypes did not influence the study results.


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The office environment can cause asthma https://parentsofallergicchildren.org/the-office-environment-can-cause-asthma/ https://parentsofallergicchildren.org/the-office-environment-can-cause-asthma/#respond Tue, 07 Sep 2021 08:14:55 +0000 https://parentsofallergicchildren.org/the-office-environment-can-cause-asthma/ New research presented today (September 6, 2021) at the ERS International Congress [1] suggests that the seemingly harmless office environment may cause asthma in some workers. The study found a variety of triggers ranging from printer toner and cleaning products to poor ventilation and mold circulating in the air conditioning. He also found that employees […]]]>

New research presented today (September 6, 2021) at the ERS International Congress [1] suggests that the seemingly harmless office environment may cause asthma in some workers.

The study found a variety of triggers ranging from printer toner and cleaning products to poor ventilation and mold circulating in the air conditioning. He also found that employees with asthma caused by office work were quitting their jobs, and if employers didn’t make changes to tackle the problem, it was more common.

Researchers say their work provides another reason for allowing home work to continue beyond COVID-19 restrictions, to benefit the health of office workers and help businesses retain staff.

The study was presented by Dr Christopher Huntley of the Birmingham Regional Occupational Lung Disease Service at the University Hospitals Birmingham NHS Foundation Trust in the UK. He said: “Any work environment can induce occupational asthma if it contains a respiratory sensitizer. This is a substance that triggers an irreversible allergic reaction, such as paint spray or dust. We generally think of an office as a safe environment, so it is possible that when asthma is diagnosed in office workers, work causes are overlooked. As a result, there has been very little research on this issue.

“However, we have increasingly diagnosed cases of occupational asthma in patients who work in offices, as well as clusters of cases in specific offices.”

Dr Huntley and his colleagues studied the cases of 47 office workers with occupational asthma who were reported to the Birmingham Regional Occupational Lung Disease Service. The majority had had their asthma confirmed by serial peak flow monitoring. This measures the fastest rate that patients can breathe air from their lungs. Seventeen of the patients had also been tested and had lungs that responded strongly to an airway sensitivity test.

Researchers identified three main categories that were causes of occupational asthma in office workers. These are triggers found inside the office (printer toner, tile adhesive, mold and cleaning products), triggers from the office ventilation system (mold in air conditioning ducts and poorly installed ventilation) and triggers in the immediate environment of the office (nearby workshops, painting and vehicle fumes).

They also looked at whether employers had made any adjustments to support office workers with occupational asthma and what workers did as a result. Their most striking finding is that when employers don’t take action, workers are 100 times more likely to quit.

Dr Huntley said: ‘Although we only looked at the patients who were referred to our department and it was a relatively small study, it was still one of the largest. studies reporting occupational asthma in office workers. We’ve discovered a few key causes to be aware of in an office environment, but there are sure to be more.

“If a worker develops occupational asthma, adjustments in the workplace can and should be made to improve asthma symptoms and help retain staff. “

Dr Huntley says there have been fewer new referrals for patients with occupational asthma during COVID-19 restrictions and those who already have occupational asthma have seen improvements while working from home. He adds: “Homework has been helpful for patients both in making their diagnosis and as a form of non-pharmacological treatment. Allowing workers with occupational asthma to continue working from home can help keep office workers in their jobs as they need fewer sick days. “

Arzu Yorgancıoğlu, who was not involved in the study, is Chairman of the Defense Council of the European Respiratory Society and Professor of Respirology at Celal Bayar University in Turkey. She said: “Because we tend to view office environments as relatively safe, compared to other professional environments where exposure to pollutants can occur, it is likely that there are more patients suffering. undiagnosed office-related asthma.

“For office workers with asthma who experience an unexplained deterioration in their symptoms, this study underscores the importance of identifying and eliminating any potential occupational triggers. When we see clusters of work-related asthma in offices, it is essential to investigate the underlying cause, as the causes can be surprising. “

Reference
Huntley C. et al. Occupational asthma in office workers: a cross-sectional study. Presented at the ERS International Congress. September 6, 2021. PA1904

This article was republished from the following materials. Note: The material may have been modified for its length and content. For more information, please contact the cited source.


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7 things that make taste buds swell https://parentsofallergicchildren.org/7-things-that-make-taste-buds-swell/ https://parentsofallergicchildren.org/7-things-that-make-taste-buds-swell/#respond Fri, 03 Sep 2021 19:16:56 +0000 https://parentsofallergicchildren.org/7-things-that-make-taste-buds-swell/ A swollen taste bud is probably caused by something you’ve eaten, but sometimes it’s a sign of another condition. Image Credit: Deagreez / iStock / GettyImages Fast: Watch your tongue. These bumps? This is called the taste buds. Most of these taste buds contain taste buds. According to Britannica, your tongue has 2,000 to 8,000 […]]]>

A swollen taste bud is probably caused by something you’ve eaten, but sometimes it’s a sign of another condition.

Image Credit: Deagreez / iStock / GettyImages

Fast: Watch your tongue. These bumps? This is called the taste buds. Most of these taste buds contain taste buds. According to Britannica, your tongue has 2,000 to 8,000 taste buds.

And, as you guessed, those taste buds can swell.

Often people don’t even know they have swollen taste buds until they have a reason to look in their own mouth, Otolaryngologist Michelle Robin Yagoda, MD, told LIVESTRONG.com (and taste bud expert) at Northwell Health in New York. .. (Like when you go for a dental cleaning, have a cold sore or a canker sore, or another family member has an oral problem, causing you to take control of yourself.)

For some people, what they find is alarming. “A lot of people come into the office saying ‘listen, I got this tongue thing and I’m afraid it’s tongue cancer,’” says Dr. Yagoda.

To see something? Here’s what could happen – and when to tell your doc something.

1. This is what your taste buds look like

What you might see is the appearance of completely normal taste buds.

There are different types of taste buds. One is the foliate papillae, which are located on the back of your tongue in an inverted V-shape, says Dr. Yagoda. These are bigger and rounder than your other heads, and you can see them clearly if you look at your tongue in the mirror.

“Being able to see those taste buds isn’t a big deal, but if they feel funny then you should get them checked out,” she says.

2. Your tongue is irritated

In response to irritation, the taste buds may swell.

“The most common causes are spicy or acidic foods,” says Dr. Yagoda. It can also happen if you eat something hot.

Fortunately, things should be back to normal shortly, without you having to do anything about it.

“The mucous membranes in the mouth turn quickly, which means they break off and develop new ones. The inflammation should go away in three to four days at most,” says Dr. Yagoda.

Another source of irritation? Acid reflux, especially if stomach acid is backing up in the mouth. (This type of tongue irritation from acid reflux would appear on the back of the tongue, says Dr. Yagoda.)

Other symptoms of acid reflux are as follows, according to the Mayo Clinic:

  • Stomach pains
  • Chest pain
  • Problems swallowing or feeling like you have a lump in your throat
  • Swallowing sour food or liquid
  • Chronic cough
  • Hoarseness or loss of voice

4. It’s oral allergy syndrome

She points to another culprit: oral allergy syndrome. If you have seasonal allergies, this is a cross reaction between allergens in pollen and certain foods (like raw fruits and vegetables). According to the American College of Allergy, Asthma & Immunology, it can also cause itchy mouth, sore throat, or swelling of the lips, mouth, tongue, or throat.

Cooking foods that trigger oral allergies can help tame symptoms.

5. It’s a dental problem

Your teeth can also chronically scratch and irritate your tongue.

“This can be dangerous over a long period of time. Chronic inflammation in the same location can predispose a person to developing abnormal cells that can become cancerous in the area,” says Dr. Yagoda.

If the problem is tooth-related, your dentist can take a smoothing burr and easily and painlessly file a rough tooth in minutes, she says.

Poor oral hygiene can also play a role in tongue and taste bud problems. Getting your teeth cleaned and plaque removal at the dentist can help, adds Dr. Yagoda. To keep your tongue in tip-top shape, gently brush the surface with a soft bristle brush, she recommends.

6. It’s a nutritional deficiency

Lack of B vitamins or low iron levels can show up as tongue problems.

“This is why it is so important that your doctor take your complete medical history and know if you have anemia or celiac disease or other disorders causing malabsorption,” says Dr. Yagoda. “Underlying medical problems can appear on the tongue.”

It is important to have a lump or new growth in your mouth examined by a doctor. And don’t assume you’d be able to tell that something was cancerous.

“When it comes to oral cancers, there is often no sensation or pain associated with these growths,” says Dr. Yagoda.

People at higher risk for oral cancer include those who smoke and drink alcohol. According to the American Cancer Society, if you are a heavy smoker and drinker, you are 30 times more likely to develop any of these cancers than non-smoker abstainers. (Cigarette smoke also irritates the taste buds, for the record.)


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Fall allergies will be in full effect in parts of the United States https://parentsofallergicchildren.org/fall-allergies-will-be-in-full-effect-in-parts-of-the-united-states/ https://parentsofallergicchildren.org/fall-allergies-will-be-in-full-effect-in-parts-of-the-united-states/#respond Tue, 31 Aug 2021 18:06:33 +0000 https://parentsofallergicchildren.org/fall-allergies-will-be-in-full-effect-in-parts-of-the-united-states/ Summer is just beginning to end and already the scent of pumpkin spice can be smelled in some cafes. However, as residents prepare for a season filled with apple picking, pumpkin carving and colorful leaves, it won’t be pumpkin spice and it will all be enjoyable for everyone. As the seasonal festivities kick in, fall […]]]>

Summer is just beginning to end and already the scent of pumpkin spice can be smelled in some cafes. However, as residents prepare for a season filled with apple picking, pumpkin carving and colorful leaves, it won’t be pumpkin spice and it will all be enjoyable for everyone. As the seasonal festivities kick in, fall allergies will also be back in force in parts of the country, affecting millions of Americans, AccuWeather forecasters say.

Meteorological fall officially begins on September 1, and astronomical fall begins on the day of the fall equinox, which will be on September 22 of this year.

Fall allergies are usually triggered by ragweed, and pollen from these types of plants common in North America can travel as far as the wind blows it. Another cause of allergies in the fall is mold, which can grow in piles of damp leaves.

According to the U.S. Centers for Disease Control and Prevention (CDC), ragweed is one of the biggest pollen producers and the biggest contributor to seasonal allergies in the fall. A ragweed plant can produce billions of pollen grains each year. About 23 million Americans suffer from seasonal allergies, commonly known as hay fever, due to the effects of ragweed, according to the American College of Allergy, Asthma and Immunology (ACAII).

According to the ACAII, allergies to falls can trigger a plethora of unpleasant symptoms, including sneezing, runny nose, congestion, itchy throat and eye irritation. The severity of these symptoms can range from mild to severe and, according to the Cleveland Clinic, can exacerbate symptoms caused by asthma.

The onset of symptoms can begin even before the first official day of fall, and the duration and intensity of symptoms can be significantly influenced by weather conditions. And, this year, distinguishing these COVID-19 symptoms caused by the delta variant could complicate matters even further.

Most areas will need a “hard frost” that lasts a few days in order to see a complete stop in the pollen season, said AccuWeather senior meteorologist Alan Reppert. Some areas will be lucky to get this freeze sooner, but some places further south might not cool down as quickly, resulting in an extended allergy season.

Those who live around the Great Lakes will be lucky if they suffer from allergies in the fall. Colder air will enter the area early, Reppert says, and while many may miss the warmer weather, it will end allergy season this fall.

In the central and southern plains, those with allergies will not be so lucky. Temperatures in the region will go up and down and are not expected to drop soon enough – or for long enough – to bring the pollen season to an early end.

The plains to the north and northwest will start to see cooler air coming in earlier than places to the south, but they can expect an average pollen season overall, with the exception of the Washington State, much of Montana and northern Idaho where pollen levels are expected to be high this fall due to persistent heat and precipitation to arrive in the area.

While the Southwest has battled drought for much of the summer, anything that can grow despite the lack of rainfall will continue to produce pollen for most of the fall.

“Drought can help the pollen season in the southwest a bit, however, as a lack of rain prevents any weeds or grass from growing,” Reppert explained.

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AccuWeather forecasters warn that while not a manual allergen, continuous smoke from wildfires can sometimes contribute to poor air quality, which could exacerbate symptoms people with respiratory, lung and heart disease and even those without pre-existing conditions in the western United States. States this fall. This season is set to rank among the five worst wildfire years on record.

A much different threat is in store for the people who live along the opposite coast of the United States. Tropical impacts are expected to continue along the east coast, and Reppert explained that the active tropical season could result in a longer allergy season from Florida to the mid-Atlantic.

“Tropical weather would mean more humidity, which would prevent vegetation from sleeping,” said Tom Kines, senior meteorologist at AccuWeather. “It would also signal warmer temperatures, which, again, would keep vegetation thriving.”

The significant amount of precipitation could also trigger more mold growth, according to Kines.

The southeast in particular is expected to experience the brunt of the seasonal sniffles, with high pollen levels in the forecast. The Gulf Coast also experiences a prolonged allergy season. “Allergy season along much of the Gulf never goes away completely,” Reppert said. “But it drops significantly” towards the start of winter.

(Tanja Ristic / iStock / Getty Images)

The fall pollen forecast for the northeastern United States is split.

In the Adirondacks and in central and northern New England, residents will likely only have to endure a short allergy season due to an early season frost that should be combined with minimum precipitation. In the southern part of New York state to the mid-Atlantic, however, the story will play out in a very different way, as above-normal humidity and tropical threats continue into the fall. will lead to a worse allergy season.

To protect yourself from the effects of pollen, the CDC recommends keeping abreast of the pollen forecast, which can be done easily by using the AccuWeather app and checking the AccuWeather.com forecast.

Kines explained that the wind plays an important role in seasonal allergies because it can move pollen hundreds of miles from the source. Wind direction is also important, especially along the coasts, he explained. For example, along the east coast, an easterly wind off the ocean can provide relief to allergy sufferers, as pollen is not carried in this case.

The CDC also recommends that people with pollen allergies avoid touching their eyes when they are outdoors, keep windows closed, shower after going out, and use air filters in the home.

People with allergies should consult an allergist on the best plan to control symptoms.

With the COVID-19 pandemic continuing in the United States, many people may fear that their allergy symptoms are in fact due to COVID-19. Additionally, evidence indicates that COVID-19 is a seasonal virus that gets worse in cold weather, meaning more people are likely to be infected as temperatures drop.

According to Dr. Murray Ramanathan, director of Johns Hopkins Otolaryngology-Head and Neck Surgery in the Greater Washington area and associate professor of otolaryngology, there are simple ways to distinguish the two sets of symptoms.

“These are two conditions that can cause very similar symptoms: stuffy nose, runny nose, sore throat, drainage,” Ramanathan told AccuWeather. “The kind of telltale signs of allergy that might be different from the symptoms of COVID-19 are really itchy eyes, itchy nose, itchy throat.”

A summer school student is tested for COVID-19 at the EN White School Nursing Office in Holyoke, Massachusetts on Wednesday, August 4, 2021. Schools across the United States are on the verge of start a new year amid a flood of money bigger than they’ve ever seen before, an injection of pandemic aid that’s four times the amount the U.S. Department of Education sends K-12 schools over the course of a typical year. (AP Photo / Charles Krupa)

“The other thing is that the allergy symptoms increase and decrease,” he explained.

While things like pollen counts can worsen or improve allergy symptoms day by day, symptoms of COVID-19 tend to gradually get worse.

The delta variant and the vaccines made spotting symptoms even more difficult.

Ramanathan said that because the virus is constantly changing and each person’s body responds to it differently, it can become more difficult to tell whether or not someone will have symptoms similar to allergies. In addition, the understanding of the symptoms of the coronavirus is constantly evolving.

With the original strain of the coronavirus, many people suffered from a fever that worked as a telltale sign that their symptoms were not related to an allergy. Ramanathan, however, said people who are vaccinated generally do not experience a fever when infected with the delta variant.

People who don’t have a fever may instead examine their other symptoms, such as loss of taste and smell, to determine if they are beyond their typical allergy symptoms.

Whether or not a person should be involved depends on the context, such as how many people they have been in contact with or whether they have been exposed, Ramanathan explained. He said that a person who recently went to a big concert may want to get tested for COVID-19 more easily than a person who was just hiking outside and exposed to allergens. According to Ramanathan, it’s “reasonable” for a person to take allergy medication to see if symptoms improve, but he advised to watch closely if symptoms worsen.

“If you feel your condition is getting worse, it is reasonable to get tested for COVID, especially if the symptoms are progressive,” he said. “The last thing you want to do is put it down to allergies and keep thinking it’s allergies and then it’s going to be COVID.”

Kcome back to AccuWeather.com and stay tuned to the AccuWeather network on DirecTV, Frontier, Spectrum, FuboTV, Philo and Verizon Fios.


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Knowing that this specific gene can cause endometriosis could lead us to better treatments https://parentsofallergicchildren.org/knowing-that-this-specific-gene-can-cause-endometriosis-could-lead-us-to-better-treatments/ https://parentsofallergicchildren.org/knowing-that-this-specific-gene-can-cause-endometriosis-could-lead-us-to-better-treatments/#respond Fri, 27 Aug 2021 20:04:48 +0000 https://parentsofallergicchildren.org/knowing-that-this-specific-gene-can-cause-endometriosis-could-lead-us-to-better-treatments/ A rigorous international investigation into the genetics of endometriosis has revealed a potential new therapeutic target for what remains a very common and incurable disease. Endometriosis occurs when tissue similar to the uterus grows outside the uterus, often causing chronic pain, but not in all cases. After decades of neglect by researchers and doctors, the […]]]>

A rigorous international investigation into the genetics of endometriosis has revealed a potential new therapeutic target for what remains a very common and incurable disease.

Endometriosis occurs when tissue similar to the uterus grows outside the uterus, often causing chronic pain, but not in all cases.

After decades of neglect by researchers and doctors, the reality is that we still know very little about this inflammatory disease, which primarily affects women of childbearing age.

Treatments currently include surgery to remove endometrial damage and hormones to control their growth, but both have imperfect results and come with their own risks and side effects.

Alternative treatments are desperately needed, and because endometriosis is often inherited, drug researchers are turning to genetics for clues.

The first parallel investigation of humans and rhesus macaques (Macaca mulatta) has now revealed a possible direction for future drug treatment; it is the one that is not based on hormones, which can lead to many side effects.

It started with a 2015 study at the University of Oxford on 32 families with at least three patients with endometriosis. Here, researchers discovered a genetic link between stage III / IV endometriosis and a region of the human chromosome called 7p13-15.

It was a good place to start, but this region alone contains hundreds of genes. In the end, it took several more years of research at Baylor College of Medicine in Texas to locate the specific gene the researchers were looking for.

When the researchers sequenced the DNA of 849 macaques – 135 of which had developed spontaneous endometriosis – they noticed a variation in the NPSR1 gene, which is located on chromosome 7p13-15 and appears to increase one’s risk of suffering from endometriosis. advanced stage.

Back in Oxford, the researchers sequenced the DNA of more than 11,000 women, including 3,000 women with endometriosis, to see if they could find a similar genetic variation in men. Their results finally revealed that stage III / IV endometriosis is associated with the same specific variant of the NPSR1 gene as that found in macaques.

In the past, variations in the NPSR1 gene have been linked to several other inflammatory conditions, such as asthma, allergies, inflammatory bowel disease (IBD), rheumatoid arthritis, and recurrent abdominal pain – some of which are known to coexist with endometriosis. .

But the variation, in this case, was slightly different from what has been found before with, say, IBD.

“It is one of the first examples of DNA sequencing in non-human primates to validate the results of human studies and the first to have a significant impact on understanding the genetics of complex and common metabolic diseases,” said Jeffrey Rogers of Baylor College of Medicine.

“The primate research has really helped build confidence in every step of genetic analysis in humans and has motivated us to keep chasing these particular genes.”

In recent years, a growing number of researchers have come to suspect that endometriosis is not just a disease, but actually consists of several different subtypes.

There has even been preliminary evidence that the different stages of endometriosis are genetically distinct, but as of yet, there are no drugs available that target these specific variations.

The advanced stages of endometriosis are generally defined by a higher number of lesions with deeper infiltration, and yet this does not always correspond to greater pain or worsening of symptoms.

The way endometriosis presents itself can vary widely from patient to patient, and no one is quite sure why or how best to treat the various symptoms.

Even in current research, not all endometriosis patients studied at the University of Oxford had an NPSR1 variant, meaning that if a drug can be developed to target this subtype, it likely won’t work. not for everybody.

Still, that doesn’t mean it’s not worth pursuing. When the researchers inhibited the expression of the NPSR1 gene in mice, which had small pieces of uterine lining implanted in their abdomen to mimic endometriosis, the animals showed signs of reduced inflammation and abdominal pain.

“We need to do more research on the mechanism of action and the role of genetic variants in modulating the effects of the gene in specific tissues,” says genetic epidemiologist Krina T. Zondervan of the University of Oxford.

“However, we have a promising new non-hormonal target for further research and development that appears to directly address the inflammatory and painful components of the disease.”

As in any emerging field, this study has its limits. A relatively small number of patients were initially studied at the University of Oxford and the functional effects of changes in the NPSR1 gene could not be studied.

While the mice appeared to see their pain decrease somewhat when this genetic variant was turned off, Stacy McAllister, an endometriosis researcher at Emory University who was not involved in the study, said Scientific journal she would like to know if the results can be extended from the relief of acute pain to the relief of chronic pain, which is the main complaint of patients with endometriosis.

Also, because mice don’t have their period, their models of this suspected inflammatory disease can’t tell us the same. The authors of the present study admit that their results do not present the “full spectrum of disease” or “pathological nuances” that we have seen in humans.

As such, they hope to conduct further research on NPSR1 variants and their functional effects in macaques. If researchers can target the gene in monkeys the same way they do in mice, we can start testing some drug treatments, progressing to clinical trials in humans.

This reality is still a long way off, but given the debilitating toll endometriosis can have on the lives and livelihoods of women around the world, it is critical that we find a better way to treat this disease.

The study was published in Science Translational Medicine.


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