Allergic Asthma – Parents Of Allergic Children http://parentsofallergicchildren.org/ Mon, 21 Nov 2022 22:37:08 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://parentsofallergicchildren.org/wp-content/uploads/2021/06/icon-5.png Allergic Asthma – Parents Of Allergic Children http://parentsofallergicchildren.org/ 32 32 Vitamin D supplements do not reduce asthma exacerbations overall – Consumer Health News https://parentsofallergicchildren.org/vitamin-d-supplements-do-not-reduce-asthma-exacerbations-overall-consumer-health-news/ Mon, 21 Nov 2022 22:37:08 +0000 https://parentsofallergicchildren.org/vitamin-d-supplements-do-not-reduce-asthma-exacerbations-overall-consumer-health-news/ MONDAY, Nov. 21, 2022 (HealthDay News) — Vitamin D supplementation does not reduce the risk of asthma exacerbation in children in general, but does reduce the risk in those with serum 25-hydroxyvitamin D levels ( 25[OH]D) concentrations, according to a review recently published in Nutrients. Qinyuan Li, MD, of the Chongqing Key Laboratory of Pediatrics […]]]>

MONDAY, Nov. 21, 2022 (HealthDay News) — Vitamin D supplementation does not reduce the risk of asthma exacerbation in children in general, but does reduce the risk in those with serum 25-hydroxyvitamin D levels ( 25[OH]D) concentrations, according to a review recently published in Nutrients.

Qinyuan Li, MD, of the Chongqing Key Laboratory of Pediatrics in China, and colleagues conducted a systematic review and meta-analysis to examine the effects of vitamin D supplementation in children with allergic diseases. Data were included from 32 randomized controlled trials ( RCTs ) comparing vitamin D supplementation with placebo in 2347 children.

The researchers found that, compared to placebo, vitamin D supplementation did not reduce the overall risk of asthma exacerbations (relative risk, 0.84; 95% confidence interval, 0.65 to 1, 08; P = 0.18), but reduced risk of asthma exacerbation in children with baseline serum 25(OH)D < 10 ng/mL (relative risk, 0.48; 95% confidence, 0.28 to 0.83; P = 0.009). A significant reduction was observed in Scoring Atopic Dermatitis or Eczema Area and Severity Index scores in children with atopic dermatitis with vitamin D compared to placebo (standardized mean difference, -0.5; 95% confidence interval , -0.87 to -0.12; P = 0.009). For children with allergic rhinitis, vitamin D supplementation reduced the symptom-medication score compared to placebo (mean, 43.7 versus 57.8).

“Large-scale, well-designed RCTs are needed to confirm these findings and investigate the optimal vitamin D regimen and which patients would benefit most from vitamin D supplementation,” the authors write.

Summary/Full text

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Do you have seasonal allergies? Pollen count is highest after 2 p.m., lowest early in the morning https://parentsofallergicchildren.org/do-you-have-seasonal-allergies-pollen-count-is-highest-after-2-p-m-lowest-early-in-the-morning/ Fri, 18 Nov 2022 21:58:30 +0000 https://parentsofallergicchildren.org/do-you-have-seasonal-allergies-pollen-count-is-highest-after-2-p-m-lowest-early-in-the-morning/ ATLANTIS — According to a new study, people who struggle with seasonal allergies prefer to go out in the morning when pollen counts are lower. Scientists report that pollen count peaks in the late afternoon and early evening, while dropping to its most tolerable level between 4 a.m. and noon. The study’s lead author, Dr. […]]]>

ATLANTIS — According to a new study, people who struggle with seasonal allergies prefer to go out in the morning when pollen counts are lower. Scientists report that pollen count peaks in the late afternoon and early evening, while dropping to its most tolerable level between 4 a.m. and noon.

The study’s lead author, Dr. Stanley Fineman of the American College of Allergy, Asthma and Immunology (ACAAI), says the findings could help people with pollen allergies enjoy the outdoors more.

“People with pollen allergies can generally benefit from knowing what time of day the pollen count is highest,” he said in a statement. “We monitored hourly pollen levels in three areas of Atlanta for a week using an automated real-time pollen imaging sensor. We found that the lower pollen levels occurred between 4:00 a.m. and noon. Higher pollen levels occurred between 2:00 p.m. and 9:00 p.m. “

According to the CDC, as many as 60 million Americans suffer from seasonal allergies, also known as hay fever. It is mainly triggered by an allergic reaction to grass pollen, which is almost impossible to avoid in spring and summer, when plants release extremely fine particles as part of their reproductive cycle.

There is currently no cure for hay fever, which is the most common name for a pollen allergy. Many people instead rely on antihistamines to reduce the symptoms of their allergic reactions, including runny nose, itchy eyes or throat, and frequent sneezing.

However, Dr. Fineman, presenting his findings at the ACAAI’s annual meeting in Kentucky, said sufferers can reduce their exposure by leaving when pollen counts are lower, which would therefore result in less of a reaction. “Every spring and fall I see patients who are really in pain because of their pollen allergies,” he says. “There are ways to lessen the impact of pollen during allergy season, including closing windows and removing pollen-laden shoes and clothes when you walk through your door, and throwing your clothes in the washing machine immediately. wash.

“If you’re someone who enjoys outdoor activities, you need to know when pollen counts are lowest and what are the best times for you to be outdoors,” he adds. “Weather apps and websites are a good way to monitor pollen levels in your area.”

South West News Service writer Danny Halpin contributed to this report.

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Allergy Skin Testing Market 2022 – Industry Growth Demand, Major Players, Key Application and Forecast to 2032 https://parentsofallergicchildren.org/allergy-skin-testing-market-2022-industry-growth-demand-major-players-key-application-and-forecast-to-2032/ Thu, 17 Nov 2022 06:24:20 +0000 https://parentsofallergicchildren.org/allergy-skin-testing-market-2022-industry-growth-demand-major-players-key-application-and-forecast-to-2032/ Allergy Skin Testing Market The latest study published by Quince Market Insights, “Allergy Skin Test Market” contains more than 400 pages of analysis on the business strategy adopted by key and emerging players in the industry and provides know-how on the current development of the market, landscape, technologies, drivers, opportunities, market view and status. In […]]]>

Allergy Skin Testing Market

The latest study published by Quince Market Insights, “Allergy Skin Test Market” contains more than 400 pages of analysis on the business strategy adopted by key and emerging players in the industry and provides know-how on the current development of the market, landscape, technologies, drivers, opportunities, market view and status. In this study, 2021 has been considered as the base year, 2022 as the estimate year and 2023 to 2032 as the forecast period to estimate the market size for Allergy Skin Testing.

This research report showcases all major systems and innovations which have recently been employed throughout the worldwide industry in the global Allergy Skin Test Market. Market prices are calculated from the point of view of the strong consumer, taking into account the main suppliers and the market economies concerned. This research study also analyzes the business growth status and potential market trends globally. Further, the global market segmentation by type, region and application is thoroughly and intensively studied and the market profile and associated outlook disclosed. Major public users fund market volumes and asset development is supported by private users. Likewise, data from major market players has been extensively presented in the research study.

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This research report also highlights leading industry players in the global Allergy Skin Testing market providing details such as company profiles, product specifications, product price, cost and will sharing, availability and communication of data. The feasibility of existing investment programs is checked and the full results of the analysis are discussed. This research also presents key statistics on the recent business situation, with tables and figures helping to report on the global market, and perhaps a key source of guidance &amp; direction. Also, it lists upstream raw materials and downstream demand analysis. comprehensively. Allergy Skin Testing Market Research Report Includes Leading Players Thermo Fischer Scientific (USA), Arlington Scientific, Inc. (USA), Cell Science Systems (USA), Quest Diagnostics Incorporated (USA), Lincoln Diagnostics, Inc. (USA), HollisterStier Allergy (US) and Novartis Global (Switzerland)

The market segment study covers market size, market sub-segments, upstream price & cost situation and business climate. The study also examines factors affecting industry growth and the concept of trade channels. The analysis begins with a description of the supply chain framework and shows the upstream one. Further, the study analyzes the market size and forecast across different geographies, categories, and end-use segments and provides an overview of market competition and key company profiles, along with a price review. of the market and the characteristics of the sales channel. The allergy skin testing market is segmented By type (prick, intradermal, patch), indication (allergic rhinitis, allergic asthma, drug allergy, anaphylaxis, urticaria, food allergy), end user (hospitals and clinics, diagnostic centers)

Regional analysis
Major regions covered in the study include North America, Europe, Asia-Pacific, Middle East and Africa and South America. During the forecast era, the North American region is expected to experience significant growth and have the highest CAGR. Expansion in the region may be due to growing demand and favorable legislation in the United States.

In terms of pages, the Allergy Skin Testing Market research report is vast and offers unique data, facts, important statistics with tables and figures, trends and competitive landscape details of this market specialized.

During the forecast period, increasing investments from major players, especially in Japan, will contribute to the development of the region. By 2032, demand will be further driven by booming Japanese industry. Government support for ongoing manufacturing projects in the region will provide an opportunistic line for regional demand. The ever-increasing demand from customers will drive the growth of the industry over the forecast period.

Primary data: Primary market research is a type of research that involves acquiring information from target industries, either through a third party or directly from customers.

Secondary data: Secondary market research is a survey strategy in which a company relies on publicly available data to learn more about its customers and target markets.

Market valuation and forecasting methodology: Market research fills the gap between a good or service and its target market or customer. Market research information helps a manufacturer or service provider develop a product or service plan that meets the specific needs of the target market.

Quantitative market research: Quantitative market research is a method of collecting data about the target market and consumers that can be quantified.

Qualitative market research: Qualitative market research is a way of collecting qualitative data about target markets through the use of instruments and procedures such as focus groups and interviews.

Product development and innovation: Detailed information on upcoming technologies, product launches as well as research and development activities in the global market.

Market penetration: In-depth information about the product portfolios of leading market players in the global Allergy Skin Testing Market.

Market Diversification: Exhaustive details about the design, development, untapped geography of the new product as well as investments in the allergy skin testing market.

Consequences of COVID-19

As it is difficult for companies to plan or make crucial business decisions in these turbulent and unpredictable times, industries are all trying to overcome them. The COVID-19 outbreak has wreaked havoc on the manufacturing and construction industries in several ways, including commodity supply and prices, worker availability, and project completion times. Raw material shortages and supply chain disruptions have had an effect on the industry.

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What does this study bring?

  • Global Allergy Skin Testing Market Forecast and Submarkets Covering the Period 2019 to 2032 with Associated Analysis
  • Detailed details and analysis of contracts, projects and programs
  • Analysis of game-changing technology trends and how they are shaping the industry
  • Explanation of policy, regulatory and technical factors to consider
  • Analysis of barriers to entry for markets around the world
  • Profiles of the main companies operating in the sector
  • SWOT analysis of major key players operating in the market along with available opportunities and major driving threads
  • Market Conclusions and Recommendations

Have a 15-minute chat with the lead analyst and report author in a time slot you’ve decided. You will be briefed on the contents of the report and questions regarding the scope of the document will also be addressed.

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Key questions answered by this report

  • How is the allergy skin testing market evolving?
  • What motivates and hinders the dynamics of allergy skin testing?
  • How will the segment of each Allergy Skin Testing submarket grow during the forecast period and how much sales will these submarkets account for in 2032?
  • How will the market shares of each of the Allergy Skin Testing submarkets grow from 2019 to 2032?
  • Which allergy skin testing submarket will be the main driver of the overall market from 2019 to 2032?
  • How will political regulatory factors influence the regional Allergy Skin Testing markets and sub-markets?
  • How will the market shares of national markets change by 2032 and which nation will lead the market in 2032?
  • Who are the key players and what is the outlook over the forecast period?
  • How will the sector evolve as a platform for alliances during the period between 2019 and 2032?

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Only 52% of adults with severe food allergies were prescribed an epinephrine auto-injector https://parentsofallergicchildren.org/only-52-of-adults-with-severe-food-allergies-were-prescribed-an-epinephrine-auto-injector/ Thu, 10 Nov 2022 04:39:26 +0000 https://parentsofallergicchildren.org/only-52-of-adults-with-severe-food-allergies-were-prescribed-an-epinephrine-auto-injector/ LOUISVILLE, KY (embargoed until November 10, 2022) – Epinephrine is the only drug that can stop anaphylaxis and it is essential that everyone with a food allergy has access to epinephrine to treat life-threatening reactions. A new study presented this year at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in […]]]>

LOUISVILLE, KY (embargoed until November 10, 2022)Epinephrine is the only drug that can stop anaphylaxis and it is essential that everyone with a food allergy has access to epinephrine to treat life-threatening reactions. A new study presented this year at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Louisville, KY shows that only half of adult food-allergic patients have immediate access to epinephrine, and 36% of adults believe that epinephrine auto-injectors (EAIs) can have negative or life-threatening effects.

“We know that not everyone who needs a pair of EAIs has easy access to them,” says Jennaveve Yost, MS, lead author of the study. “Given that food allergy affects more than 32 million people in the United States, we wanted to know why more people were not wearing AEIs for their food allergy. Our survey of over 1,000 adults showed that the top reported reason for not having an AEI was ‘my doctor didn’t say it was really needed’ or ‘I don’t think I need it’ – indicating that gaps in education present a notable barrier to Access EAI.

An online survey was conducted among 1,006 food-allergic adults. Participants identified as 61% Caucasian, 16% Black, 15% Hispanic and 7% Asian, Native American or other.

“People with food allergies and other severe allergies that can cause anaphylaxis should understand that epinephrine is the first line of defense,” says Erin Malawer, lead author of the study. “The fact that 36% of adults believe that AIEs can cause life-threatening side effects is concerning. Our goal in doing the study was to show that more people need to be informed that if they have a food allergy they should always wear an AIS and that these AIS are safe to use. Only 33% of respondents said they had an unexpired EAI, another concerning statistic. AEDs should be a current and accessible prescription.

Anyone with a food allergy should be seen by an allergist. An allergist can create a plan to help patients identify their food allergens and avoid triggers.

Abstract Title: Use and Access to Epinephrine Auto-Injector in a Nationally Representative Sample of Food-Allergic Adults
Presenter: Jennaveve Yost, MS

For more information on severe allergies and anaphylaxis, or to find an allergist in your area, visit AllergyandAsthmaRelief.org. The ACAAI Annual Scientific Meeting takes place November 10-14. For more news and research from the ACAAI Scientific Meeting, head to our newsroom – and follow the conversation on Twitter #ACAAI22.

About the ACAAI
The ACAAI is a professional medical organization of more than 6,000 allergist-immunologists and allied health professionals, headquartered in Arlington Heights, Illinois. The College fosters a culture of collaboration and friendliness in which its members work together and with others toward the common goals of patient care, education, advocacy and research. ACAAI allergists are board-certified physicians trained to diagnose allergies and asthma, administer immunotherapy, and provide patients with the best treatment results. For more information and to find relief, visit AllergyandAsthmaRelief.org. Join us on Facebook, Pinterest and Twitter.

Back to the press room

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Brooklyn Bedding Talalay Latex Pillow Review https://parentsofallergicchildren.org/brooklyn-bedding-talalay-latex-pillow-review/ Fri, 04 Nov 2022 15:30:54 +0000 https://parentsofallergicchildren.org/brooklyn-bedding-talalay-latex-pillow-review/ Brooklyn Bedding Talalay Latex Pillow Review In Brief We tested the Brooklyn Bedding Talalay latex pillow to see how it compares to other best pillows on the market. This pillow is made of latex with an organic cotton cover and designed to provide a natural and healthy sleeping experience. It comes in two different lofts […]]]>

Brooklyn Bedding Talalay Latex Pillow Review In Brief

We tested the Brooklyn Bedding Talalay latex pillow to see how it compares to other best pillows on the market. This pillow is made of latex with an organic cotton cover and designed to provide a natural and healthy sleeping experience. It comes in two different lofts – a low loft (the one we tested and recommend for back or front sleepers) or a high loft (which would be better for side sleepers).

Brooklyn Bedding Talalay Latex Pillow Specifications

Type: latex pillow
Best suited to: Sleepers on the belly and on the back (low loft version), side sleepers (high loft version); allergic people, hot sleepers
Trial period: 30 days
Guarantee: 3 years

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Kit Connor tweets that he’s bisexual https://parentsofallergicchildren.org/kit-connor-tweets-that-hes-bisexual/ Tue, 01 Nov 2022 21:50:04 +0000 https://parentsofallergicchildren.org/kit-connor-tweets-that-hes-bisexual/ Kit Connor is best known for playing Nick in the Netflix LGBTQ+ romantic comedy “Heartstopper,” which follows teens as they navigate school, feelings, and sexualities. While the series itself shines a light on LGBTQ+ characters in a beautifully authentic way – giving many of them plenty of room to come out at their own pace […]]]>

Kit Connor is best known for playing Nick in the Netflix LGBTQ+ romantic comedy “Heartstopper,” which follows teens as they navigate school, feelings, and sexualities. While the series itself shines a light on LGBTQ+ characters in a beautifully authentic way – giving many of them plenty of room to come out at their own pace – the compassionate message behind the series seems to have been lost on many. , as evidenced by Connor’s recent post.

The ‘Rocketman’ star wrote a tweet late on October 31, announcing he was bisexual, but added that he felt compelled to come out after being harassed by fans. The actor wrote, “Back a minute. I’m bi. Congratulations on forcing an 18 year old to come out. I think some of you missed the point of the show. Goodbye.”

Moments after Connor’s tweet, supportive comments flooded his timeline, both with love for the star and anger at the circumstances under which he felt he had to make the announcement. Favorite Writer Alice Oseman responded by tweeting“I really don’t understand how people can watch Heartstopper and then happily spend their time speculating about sexualities and judging based on stereotypes. I hope all these people are embarrassed like F*CK. Kit, you are amazing 💖.”

Joe Locke, his “Heartstopper” bandmate who plays Charlie, responded while tweeting, “You don’t owe anyone anything. I’m so proud of you my friend 💕.” Kizzy Edgell, who plays Darcy Olsson, tweeted“I love you, I’m sorry this was so gross for you. I was treated so unfairly,” while co-star Sebastian Croft, who plays Ben Hope, wrote“Kit Connor, the world doesn’t deserve you. I love you my friend ❤.”

The toxicity that prompted Connor’s tweet was largely due to the fact that he had been accused of queerbaiting by fans following photos of him holding hands with his co-star in ‘A Cuban Girl’s Guide to Tea and Tomorrow,” queer actress Maia Reficco. Due to disturbing comments directed at the actor, he quit Twitter in September, writing, “This is a dumb app. Kinda bored now, deleting twitter :)”, but he made a short-lived comeback to set the record straight. on time.

Connor had also previously spoken about unnecessary speculation surrounding his sexuality and his discomfort with being labelled. “To start speculating about our sexualities and maybe pressuring us to come out when we might not be ready. For me, I feel completely confident and comfortable with my sexuality,” he said. said on the “Reign With Josh Smith” podcast. in May. “But I don’t feel the need to really, you know – I’m not too big on labels and things like that. I’m not massive about it.”

Many fans were quick to respond to Connor’s tweet and express their frustration. “Reading tweets like this is heartbreaking…especially when Heartstopper has taught so many around the world the true value of someone’s personal story. I’m so sorry that this moment was taken away from you, Kit, but hopefully people will. learn from it!” we wrote. Another one tweeted“I’m so disappointed in this fandom.”

Connor himself summed up the bizarre phenomenon of judging, labeling, and unwarranted theories about those in the public eye. “It’s a little strange to make assumptions about someone’s sexuality just by hearing their voice or seeing their appearance. I feel like that’s a very interesting and slightly problematic assumption to make,” did he declare.

Again, we are reminded that celebrities are also human; fans are not entitled to everything. No one should feel pressured to come out publicly before they are comfortable doing or saying it, especially a teenager.

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Fall allergens that can sneak up on you https://parentsofallergicchildren.org/fall-allergens-that-can-sneak-up-on-you/ Thu, 27 Oct 2022 05:17:44 +0000 https://parentsofallergicchildren.org/fall-allergens-that-can-sneak-up-on-you/ Allergy and asthma symptoms do not only appear in spring and summer. The fall can cause sneezing and difficulty breathing, as can unstable weather conditions and other environmental factors. Allergy sufferers may experience frequent symptoms during the fall, although they are mainly allergic to pollens in the spring and summer. Sometimes the symptoms are the […]]]>

Allergy and asthma symptoms do not only appear in spring and summer. The fall can cause sneezing and difficulty breathing, as can unstable weather conditions and other environmental factors.

Allergy sufferers may experience frequent symptoms during the fall, although they are mainly allergic to pollens in the spring and summer.

Sometimes the symptoms are the result of a natural event. For example, the eruption of the Tonga volcano in January sent particles and aerosols into the atmosphere that can alter global weather systems, potentially lengthening or shortening pollen seasons.

The seasons could be even longer this year in the northern hemisphere, where the year saw much hotter and drier conditions than normal.

Hurricane season is in full swing and these tropical storms can produce lots of rain and destroy vegetation. This can lead to fungal “blooms” that increase mold spores in the area, which can worsen allergy or asthma symptoms for months.

Cold fronts that trigger thunderstorms can also stir up ragweed and pollen from previous seasons that have traveled long distances.

People with mold-related asthma run the risk of symptoms becoming significantly worse, which can pose a health threat. Stay indoors after storms and if there is water damage, get it repaired as soon as possible to prevent mold growth.

Try to leave your allergies outside. Showering after being outdoors and removing and washing any clothing worn outside can help limit allergens that follow you indoors.

If you have symptoms, there are several treatment options, including over-the-counter antihistamines, nasal rinses, and allergy shots, which are a form of immunotherapy. Talk to your doctor about the best options for you.

A number of factors can cause more intense allergies and extend the season into the fall. Be prepared to breathe easily.

Mat Lecompte is a health and wellness reporter for Bel Marra Health, which first published this article.

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Having started as a journalist over 10 years ago, Mat has not only honed his belief system and approach with hands-on experience, but has also worked closely with nutritionists, dietitians, athletes and health professionals. fitness. He embraces natural healing methods and believes that diet, exercise and willpower are the foundation of a healthy, happy, drug-free existence.

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Epstein-Barr virus reactivation may contribute to long COVID fatigue https://parentsofallergicchildren.org/epstein-barr-virus-reactivation-may-contribute-to-long-covid-fatigue/ Mon, 24 Oct 2022 15:35:35 +0000 https://parentsofallergicchildren.org/epstein-barr-virus-reactivation-may-contribute-to-long-covid-fatigue/ October 24, 2022 2 minute read ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=subscribe> Subscribe We have not been able to process your request. Please try again later. If you […]]]>

October 24, 2022

2 minute read


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According to a letter published in Allergy.

Up to 10% of patients with COVID-19 develop long COVID, Johanna Rohrhofer, MRS, Doctoral student at the Institute for Pathophysiology and Allergy Research, Medical University of Vienna, and his colleagues wrote.

Data are from Rohrhofer J, et al. Allergy. 2022;doi:10.1111/all.15471.

Although Epstein-Barr virus (EBV) has been associated with post-viral fatigue, the researchers said the mechanisms that lead to post-viral fatigue syndrome in general and long COVID in particular are unresolved. .

Researchers hypothesized that long COVID-induced fatigue could be triggered by persistence of SARS-CoV-2 in the gastrointestinal or respiratory tract after acute illness or by reactivation of COVID-associated EBV -19.

The study involved 30 patients (mean age, 37.73 years ± 9.96; 73.4% female) with long-lasting COVID and suffering from persistent fatigue, post-exertional malaise, autonomic dysfunction and /or orthostatic intolerance.

The researchers collected stool, throat washes and blood samples from these patients between 74 and 471 days (median, 235 days) after the onset of their acute SARS-CoV-2 infections.

The study also included 20 age- and sex-matched patients (mean age, 33.9 years ± 11.95; 65% female) who had fully recovered from acute SARS-CoV infection -2 as controls, with stool, throat washing and blood samples taken from them between 106 and 571 days (median, 275 days) after their infections began.

SARS-CoV-2 infections were mild in both groups and occurred between spring 2020 and fall 2021. There were no hospitalizations for any of these patients.

The researchers found no SARS-CoV-2 RNA in any of the throat wash or stool samples.

Additionally, there were no differences in SARS-CoV-2 IgA or IgG antibody titers between the cohorts. The researchers noted that 24 of 30 patients with long COVID and 17 of 20 controls received the COVID-19 vaccination after developing the disease but before samples were taken.

Blood and stool samples were all negative for EBV, while throat wash samples from 15 (50%) long-COVID patients and four (20%) controls were positive for EBV DNA. ‘EBV (P = 0.0411). EBV load levels did not differ significantly between groups.

With the exception of one patient in the control group, all patients in the study had previous EBV infections. The researchers concluded that the EBV replication they observed was caused by EBV reactivation and not by primary infection. Additionally, the groups had no difference in EBV-specific antibody titers.

Overall, the researchers said they detected no persistence of SARS-CoV-2 in any of the study participants up to 10 weeks after infection, although patients with or without long COVID fatigue had more EBV reactivation in their throats months after acute SARS. -CoV-2 infection.

These results indicate that cofactors of long fatigue due to COVID may include EBV replication, the researchers wrote, adding that they did not assess human leukocyte antigen subtype or other factors. contributory.

The researchers acknowledged that they could not confirm previous reports of differences in EBV antibody profiles in patients with long COVID and that additional and larger studies are needed to clarify the impact and mechanism of the long COVID fatigue associated with EBV.

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Corticosteroid therapy and bronchodilator therapy may improve symptoms in children with long-term COVID https://parentsofallergicchildren.org/corticosteroid-therapy-and-bronchodilator-therapy-may-improve-symptoms-in-children-with-long-term-covid/ Fri, 21 Oct 2022 18:13:34 +0000 https://parentsofallergicchildren.org/corticosteroid-therapy-and-bronchodilator-therapy-may-improve-symptoms-in-children-with-long-term-covid/ October 21, 2022 3 minute read ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=subscribe> Subscribe We have not been able to process your request. Please try again later. If you […]]]>

October 21, 2022

3 minute read


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According to a recent case report, daily treatment with inhaled corticosteroids and bronchodilators may help children with reversible peripheral airway obstruction and pulmonary hyperinflation after developing persistent dyspnea despite normal spirometry.

This dyspnea often develops after infection with SARS-CoV-2, Nathan Rabinovitch, MD, MPH, pediatric allergist and immunologist at National Jewish Health, and colleagues wrote in the study, published in The Journal of Allergy and Clinical Immunology: In Practice.

Physicians should assess children with post-COVID dyspnea and exercise intolerance for reversible small airway obstruction and pulmonary hyperinflation, the researchers suggested. Source: Adobe Stock

The case study

In the case study, researchers described a 17-year-old Hispanic boy who developed COVID-19 in November 2020. Symptoms included severe shortness of breath and decreased exercise tolerance that persisted through next 5 months.

The prescribed treatment started with a fluticasone metered dose inhaler (MDI) 110 and an albuterol MDI, then changed to a fluticasone/salmeterol 115 MDI. However, the patient’s compliance was poor and he took his inhalers without using a spacer.

But the patient still reported an improvement in his exercise tolerance when he took his medication, and the researchers reported that he was able to walk on a treadmill for 5 minutes before shortness of breath set in. begin.

The patient had no previous diagnosis of asthma, episodes of wheezing or recurrent bronchitis. In addition, skin tests for 23 aeroallergens were negative. Evaluation by a behavioral specialist revealed no significant anxiety or depression.

Other presentations included normal FEV11 predicted percentage (97%) and FEV11 to forced vital capacity (0.81).

According to the researchers, 7.5 minutes of cycling exercise test reproduced the patient’s dyspnea symptoms via real-time laryngoscopy without any significant decrease in FEV1.1hyperventilation or adduction of the vocal cords.

The patient also had moderately increased hyperinflation (149%) with a normal residual volume (RV) to total lung capacity (TLC) ratio of 24 via plethysmography.

In addition, the patient had a percent increase in peripheral airway resistance (44% of total airway resistance) based on resistance measurement at 5 Hz – 20 Hz (R5-R20).

The researchers considered his 56% decrease from baseline in small airway reactance, measured by the area under the curve of R5 at the resonance frequency (AX), to be also significantly reversible.

The patient was then prescribed two puffs of fluticasone 44 daily and two puffs of albuterol before exercise in addition to using proper spacing technique, while slowly increasing his exercise regimen.

Three months later, the patient was able to exercise vigorously with marked improvements in shortness of breath. Although his AX response to albuterol continued to be significantly elevated, with a 51% decrease from baseline, his R5-R20/R5 decreased to 12.5% ​​of total lung resistance.

The researchers then concluded that the obstruction and hyperinflation of this patient’s predominantly small airways contributed to his dyspnea and exercise intolerance.

Other patients, recommendations

This patient was one of 50 children with post-COVID dyspnea assessed by the researchers, most demonstrating increased RV and/or RV/TLC, elevated R5-R20/R5 or AX reversibility with albuterol.

The researchers also noted that FEV1 methacholine reactivity was sometimes present in these children, although most of them did not have low FEV11 percent predicted or significant FEV11 reversibility after albuterol.

Most of these patients had no previous diagnosis of asthma or treatment with asthma medication. Those who did had non-persistent asthma before COVID-19, and only one had taken corticosteroids daily.

Overall, these children showed improvement in small airway resistance with albuterol and/or pulmonary hyperinflation, with nearly all reporting at least partial improvements in dyspnea and improvements in antihypertensive intolerance. exercise with inhaled corticosteroid therapy, with or without long-acting beta-2 agonists.

Although R5-R20 levels also decreased in these patients, the researchers continued, they did not normalize in all cases, indicating potential long-term changes in the airways.

Symptoms continued to decrease in these children as they maintained their medication and exercise regimens, but some of these improvements were likely due to the natural course of the disease as well, the researchers wrote.

Based on these findings, the researchers recommended that the potential contribution of reversible small airway obstruction and pulmonary hyperinflation be assessed in children with post-COVID dyspnea and exercise intolerance, as well as anxiety, dysautonomia and vocal cord dysfunction.

Physicians should also initiate sustained trials of asthma medications and slowly increase exercise intensity in patients who meet these criteria, as their spirometry is often normal, the researchers concluded.

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ALK sends 60 delegates to Dublin for three-day allergy meeting https://parentsofallergicchildren.org/alk-sends-60-delegates-to-dublin-for-three-day-allergy-meeting/ Wed, 19 Oct 2022 08:36:41 +0000 https://parentsofallergicchildren.org/alk-sends-60-delegates-to-dublin-for-three-day-allergy-meeting/ More than 60 delegates from Danish pharmaceutical company ALK (Allergology Laboratory Kopenhagen) traveled to Dublin last month for a three-day meeting titled ‘Helping more allergy sufferers get better care’. ALK is a global, research-driven pharmaceutical company focused on the prevention, diagnosis and treatment of allergies. A world leader in allergy, ALK specializes in allergy immunotherapy, […]]]>

More than 60 delegates from Danish pharmaceutical company ALK (Allergology Laboratory Kopenhagen) traveled to Dublin last month for a three-day meeting titled ‘Helping more allergy sufferers get better care’.

ALK is a global, research-driven pharmaceutical company focused on the prevention, diagnosis and treatment of allergies. A world leader in allergy, ALK specializes in allergy immunotherapy, which not only reduces allergic symptoms, but also treats the underlying cause of specific allergies.

This is the first time teams from these areas have met since 2019 due to Covid travel restrictions. The meeting was also attended by ALK’s Executive Vice Presidents, Søren Niegel and Søren Jelert, and Sean Connor, Regional Managing Director for Northern Europe.

Denmark’s Ambassador to Ireland, Lars Theusen, who recently left the UK, opened the meeting and welcomed delegates to Dublin.

ALK has been represented in Ireland since 2015, however in recent years the sales team has expanded. The growth came as the company successfully obtained marketing authorization for three new allergy immunotherapy treatments in Ireland, including one for the treatment of allergic asthma in adults.

The prevalence of asthma in Ireland is among the highest in the world. It is the most common chronic disease in children and the most common chronic respiratory disease in adults. There is one death a week from asthma in Ireland.

ALK is also committed to increasing allergy education through the support of an educational grant to University College Cork. Emphasis will be placed on education through postgraduate allergy training courses.

ALK was also one of the few companies to sponsor the European Academy of Allergy and Clinical Immunology Summer School on Food Allergy. This event was recently organized at University College Cork with the participation of around 150 delegates from across Europe.

Sean Connor, Managing Director of ALK in the UK, said: “ALK is committed to improving the health of allergy sufferers around the world and to ensuring that health inequalities are minimised. In Ireland we see a large number of people who do not have access to life-changing allergy medication compared to the rest of Europe. ALK intends to change this injustice and has registered three new products in the last two years for which we are actively seeking reimbursement so that all patients can access these medicines.

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